NO!
https://www.rvtravel.com/can-i-use-a-we ... -rv-power/
These plugs are different, to help stop this from happening.
It will end badly for you. Not only are the plugs different, the circuit is as well. A 50a-RV has two hots and a neutral. A household 220 does not.
The above article from rvtravel is great, from 2018